MediHealth Direct

Zyban

Prescription-only medicine · General · UK online pharmacy

Zyban is a prescription medication clinically proven to help people quit smoking. Approved by both the NHS and FDA, Zyban increases your chances of quitting successfully by reducing cravings and withdrawal symptoms such as irritability, bad moods, and restlessness.

Key facts

Zyban prices by dose and pack size

StrengthPack sizePrice
150 mg60 pack£56.24
150 mg120 pack£101.24

Prices correct as of 2026-08-21. The exact dose is confirmed during the clinical assessment.

Zyban: Effective Medication for Quitting Smoking

What is Zyban?

Zyban is a prescription medication clinically proven to help people quit smoking. Approved by both the NHS and FDA, Zyban increases your chances of quitting successfully by reducing cravings and withdrawal symptoms such as irritability, bad moods, and restlessness.

Zyban is not a nicotine replacement therapy but works to reduce the brain’s dependency on nicotine, making it easier to quit for good.

How Does Zyban Work?

When you smoke, nicotine stimulates dopamine production in your brain. Dopamine is often referred to as the “happy hormone” and contributes to the pleasurable effects associated with smoking. However, when you quit smoking, the drop in dopamine levels causes cravings and withdrawal symptoms.

Zyban contains the active ingredient bupropion hydrochloride, which helps regulate dopamine levels in your brain. This reduces the euphoric effects of nicotine, making cigarettes less rewarding and helping you to manage cravings.

How to Take Zyban

It’s important to follow the dosage instructions provided by your healthcare professional or pharmacist. Here are the general guidelines for taking Zyban:

Instructions for Adults Under 65

  1. Week 1:
    • Days 1–3: Take one 150mg tablet daily.
    • Days 4–6: Take two 150mg tablets daily, with at least 8 hours between doses.
  2. Week 2 and Beyond:
    • Continue taking two 150mg tablets daily.
    • Choose a ‘quit day’ during this week and stop smoking.
  3. After 7 Weeks:
    • If you are still smoking, consult your healthcare professional for further advice.

Instructions for Adults Over 65

Additional Dosage Tips

What Are the Possible Side Effects?

Zyban is generally well-tolerated, but like all medications, it may cause side effects. Common side effects include:

Rare But Serious Side Effects

If you experience any of these, stop taking Zyban and contact your healthcare professional immediately.

Who Can Use Zyban?

Zyban is suitable for most adults looking to quit smoking, but some people should avoid it.

You Should Not Take Zyban If You:

Precautions

How to Buy Zyban Online

You can buy Zyban safely and conveniently online from Medihealth Direct. Simply complete a confidential online consultation, which will be reviewed by a registered healthcare professional. Once approved, your medication will be dispatched with free next-day delivery.

Zyban FAQs

What Is Zyban Used For?

Zyban is a prescription treatment used to help people quit smoking by reducing cravings and withdrawal symptoms.

How Long Does Zyban Take to Work?

Zyban typically starts working within a week. It is recommended to set a ‘quit day’ during your second week of treatment.

Is Zyban the Same as Wellbutrin?

Zyban and Wellbutrin contain the same active ingredient (bupropion hydrochloride) but are used for different purposes. Zyban is for smoking cessation, while Wellbutrin is an antidepressant.

Does Zyban Cause Weight Gain?

Zyban is not associated with weight gain. If you’re concerned about this, consult your healthcare professional.

Is It Safe to Buy Zyban Online?

Yes, buying Zyban from Medihealth Direct is safe. The service follows strict UK regulations, and all consultations and prescriptions are reviewed by registered healthcare professionals.

Can I Drink Alcohol While Taking Zyban?

It is advised to limit alcohol intake, as drinking can increase the likelihood of side effects like seizures.

How does the online consultation for Zyban work?

  1. Complete a confidential online health questionnaire.
  2. A GPhC-registered pharmacist reviews your answers and confirms whether the treatment is clinically appropriate.
  3. If approved, your medication is dispensed by the pharmacy and delivered in discreet packaging by tracked UK delivery.

See how the service works or browse all treatments.