Champix

Prescription-only medicine · General · UK online pharmacy

Champix (varenicline) is a clinically proven prescription medication designed to help individuals quit smoking permanently. It offers the highest success rate compared to other smoking cessation methods, such as nicotine replacement therapy (NRT), e-cigarettes, and counselling. Champix works by reducing nicotine cravings and withdrawal symptoms, making it easier to quit smoking.

Key facts

• Classification: Prescription-only medicine (POM) in the UK
• Treatment category: General
• Price (if prescribed): from £44.99
• Typical supply: 28 days
• Availability: Available following an online consultation
• Prescriber review: every order is assessed by a GPhC-registered pharmacist

Champix prices by dose and pack size

Prices correct as of 2026-08-21. The exact dose is confirmed during the clinical assessment.

Champix: The Most Effective Smoking Cessation Treatment

What is Champix?

Champix (varenicline) is a clinically proven prescription medication designed to help individuals quit smoking permanently. It offers the highest success rate compared to other smoking cessation methods, such as nicotine replacement therapy (NRT), e-cigarettes, and counselling. Champix works by reducing nicotine cravings and withdrawal symptoms, making it easier to quit smoking.

Why Choose Champix for Smoking Cessation?

Champix provides several benefits for those looking to quit smoking, including:

• Effective in two weeks: Many users quit smoking within the first two weeks.
• Reduces nicotine cravings: Mimics the effects of nicotine without exposure to harmful chemicals.
• Minimises withdrawal symptoms: Alleviates irritability, headaches, and insomnia associated with quitting.
• Clinically proven success: Twice as effective as other methods.
• Non-nicotine treatment: Unlike patches or gum, Champix contains no nicotine.
• Customisable support: This can be combined with other methods like NRT or counselling for better results.

How Does Champix Work?

Champix contains the active ingredient varenicline, which targets nicotine receptors in the brain. It works in two ways:

1. Reduces cravings: Varenicline mimics the effects of nicotine, satisfying the brain’s dependency without the harmful substances in cigarettes.
2. Blocks pleasure response: If you smoke while taking Champix, it reduces the pleasurable effects, discouraging the habit further.

How to Take Champix

Choosing a Quit Date

• Start taking Champix one week before your quit date to build its effectiveness.
• Alternatively, begin taking Champix and select a quit date within 8 to 35 days.

Dosage Guidelines

• Full course duration: 12 weeks, with the option for a second course if needed.
• Important: Take the tablet with a full glass of water.

Missed Dose

• If you forget to take a tablet, take it as soon as you remember.
• If it’s close to your next dose, skip the missed one. Never double the dose.

Benefits of Using Champix

• Quick Results: Most users notice significant improvements within the first two weeks.
• Long-Term Impact: A second course increases quitting success rates from 50% to 70%.
• Holistic Support: This can be combined with NHS resources, support groups, and other methods.

Champix vs. Zyban (Bupropion)

While both medications are nicotine-free, Champix outperforms Zyban in clinical trials:

• Effectiveness: Champix helps 45% of users quit smoking within 12 weeks, compared to 23% with Zyban.
• Mechanism: Zyban works as an antidepressant, whereas Champix directly targets nicotine receptors.

Potential Side Effects

Like all medications, Champix can cause side effects, though most are mild and temporary.

Common Side Effects

• Nausea
• Constipation or diarrhoea
• Insomnia or unusual dreams
• Dizziness

Rare but Serious Side Effects

• Chest pain, shortness of breath
• Allergic reactions, such as skin rash or swelling
• Mood changes, including depression or anxiety

If you experience severe side effects, stop taking Champix and seek medical advice immediately.

Precautions When Using Champix

Who Should Avoid Champix?

• Pregnant or breastfeeding women.
• Individuals under 18 years old.
• Those with a history of severe mental health issues, such as depression or schizophrenia.

Alcohol Warning

• Alcohol intake can enhance Champix’s side effects. Drink moderately or avoid alcohol during treatment.

Drug Interactions

Inform your healthcare professional about other medications you’re taking, such as:

• Insulin
• Warfarin
• Certain asthma medications

Can I Buy Champix Online?

Yes, Champix is available online from Medihealth Direct. To purchase, complete a simple online consultation reviewed by a registered healthcare professional. Once approved, your prescription will be dispensed and delivered discreetly, often the next day.

Champix FAQs

How effective is Champix?

Champix doubles your chances of quitting compared to no help, with a 45% success rate after 12 weeks.

Can Champix be combined with NRT?

Yes, Champix can be used alongside NRT options like patches or gum, but consult your healthcare professional first.

Can I drink alcohol while taking Champix?

Yes, but alcohol can amplify side effects such as dizziness or nausea.

How long does Champix stay in your system?

Champix can remain in your system for up to four days after your last dose.

Can I take Champix again if I relapse?

Yes, a second course can significantly improve long-term success rates.

How does the online consultation for Champix work?

1. Complete a confidential online health questionnaire.
2. A GPhC-registered pharmacist reviews your answers and confirms whether the treatment is clinically appropriate.
3. If approved, your medication is dispensed by the pharmacy and delivered in discreet packaging by tracked UK delivery.

See how the service works or browse all treatments.