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Desloratadine

Desloratadine is a prescription antihistamine that effectively treats allergy symptoms, including hay fever (allergic rhinitis) and indoor allergies such as dust mites, pet dander, and mould. It also helps alleviate skin allergies, including hives, rashes, and itching.

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Dose guides: 5 mg

1
£13.495 mg · 30 pack

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Desloratadine 5mg product packaging

Medically reviewed by Muhammad Abdul Jalil, Superintendent Pharmacist · GPhC Reg No: 2236161

Last reviewed

Desloratadine: Effective Allergy Relief

What is Desloratadine?

Desloratadine is a prescription antihistamine that effectively treats allergy symptoms, including hay fever (allergic rhinitis) and indoor allergies such as dust mites, pet dander, and mould. It also helps alleviate skin allergies, including hives, rashes, and itching.

This non-drowsy antihistamine provides 24-hour relief with just one daily 5mg tablet, making it a convenient solution for allergy sufferers.

What Are the Benefits of Desloratadine?

Desloratadine stands out from other antihistamines due to its unique features:

  • Fast-acting: Works within 75 minutes.
  • Long-lasting: Offers full-day relief with just one tablet.
  • Non-drowsy: Minimal sedative effects compared to older antihistamines.
  • Comprehensive: Relieves nasal, eye, and skin symptoms.

It is especially helpful for those dealing with multiple allergy symptoms, such as sneezing, itchy eyes, and skin irritation.

How Does Desloratadine Work?

Desloratadine is part of a class of medications called antihistamines, which work by blocking histamine, a chemical your body releases when exposed to allergens.

Histamine is responsible for symptoms such as:

  • Sneezing
  • Runny or blocked nose
  • Itchy eyes
  • Skin rashes

By preventing histamine from binding to receptors, Desloratadine reduces these symptoms and provides relief.

How to Take Desloratadine?

Dosage Instructions

  • Standard Dose: One 5mg tablet daily.
  • Timing: Take in the morning for full-day protection, especially during high pollen counts.
  • Administration: Swallow the tablet whole with water; it can be taken with or without food.

Missed Dose:

If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed dose—do not double up.

Overdose:

If you take more than the recommended dose, consult your healthcare professional immediately, although serious side effects are unlikely.

How to Prevent Hay Fever Symptoms?

In addition to Desloratadine, you can reduce allergy symptoms by:

  • Monitoring Pollen Count: Check daily updates online or via apps.
  • Wearing Wraparound Sunglasses: Prevents pollen from irritating your eyes.
  • Showering After Outdoor Activities: Removes pollen from hair and skin.
  • Keeping Windows Closed: Minimises exposure to allergens indoors.
  • Vacuuming and Dusting Regularly: Eliminates pollen or pet dander.
  • Avoiding High-Histamine Foods: Certain fermented or cured foods can worsen symptoms.

Possible Side Effects of Desloratadine

Common Side Effects:

  • Dry mouth
  • Lack of energy
  • Headache

Rare Side Effects:

  • Allergic reactions (swelling, difficulty breathing, or rash)
  • Severe drowsiness

If you experience serious side effects, stop taking Desloratadine and consult your healthcare professional immediately. For a full list of side effects, refer to the patient information leaflet.

Who Can Use Desloratadine?

Desloratadine is suitable for:

  • Adults and children with seasonal allergies (e.g., hay fever).
  • Individuals with year-round allergies to dust, mould, or pet dander.

Who Should Not Use It:

  • Pregnant or breastfeeding individuals.
  • Those allergic to Desloratadine or Loratadine.

Consult your healthcare professional if you have kidney issues or a history of seizures before taking this medication.

Comparing Desloratadine with Loratadine

Common Side Effects:

DesloratadineLoratadine
Potent antihistamineLess potent antihistamine
Suitable for moderate symptomsSuitable for mild symptoms
Dosage: 5mg once dailyDosage: 10mg once daily
Non-drowsyNon-drowsy

While both medications are effective, Desloratadine provides stronger relief for moderate allergy symptoms.

How to Buy Desloratadine Online?

You can order Desloratadine from Medihealth Direct after completing a quick and confidential online consultation. Our healthcare professionals will assess your medical history to ensure the treatment is appropriate for you.

Once approved, your medication will be dispatched with next-day delivery in discreet packaging.

Desloratadine FAQs

Which is better, Cetirizine or Desloratadine?

Both are effective antihistamines, but Cetirizine is more likely to cause drowsiness. Desloratadine is generally better for those who want non-drowsy relief.

Can Desloratadine make you feel sleepy?

It is a non-drowsy antihistamine, but a small percentage of users may feel slightly sleepy.

Can I use Desloratadine with other hay fever treatments?

Yes, it can be combined with nasal sprays or eye drops for severe symptoms. Always consult your healthcare professional before using multiple treatments.

Is Desloratadine available over the counter?

No, it is a prescription-only medication. However, a milder alternative, Loratadine, is available without a prescription.

Transparent pricing

The price you see is the price you pay, no hidden fees.

From
£13.49
Pack size comparison
5 mg
  • 30 pack£13.49
  • 60 pack£18.74
  • 90 pack£22.49
What's included
  • Online consultation & prescription from a UK clinician
  • Discreet, tracked deliveryRoyal Mail tracked delivery is £2.99 per order, added at checkout.
  • Ongoing clinical support from our pharmacy team

You're only charged after a prescriber approves your consultation. If it's not right for you, you're not charged.

Delivery & packaging

  • Royal Mail tracked delivery
    £2.99 per order
  • Next-day
    Order by 2pm Monday to Friday and an approved order is dispatched the same day for next-working-day delivery.
  • Packaging
    Every parcel is plain and unbranded; temperature-sensitive medicines travel in insulated cold-chain packaging at no extra cost.

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