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Epiduo Gel

Epiduo Gel is a topical acne treatment specifically designed for acne vulgaris, a common skin condition characterised by blackheads, whiteheads, papules, and pustules. It is a combination medication containing adapalene (a retinoid) and benzoyl peroxide (an antimicrobial agent), making it a powerful dual-action solution for acne.

Choose your dose

Dose guides: 0.1% / 2.5%

1
£59.990.1% / 2.5%

Your card is authorised at checkout. You’re charged only after pharmacist approval. Your delivery charge and full total are shown before you confirm payment.

Prescription medication: subject to clinical review by a GPhC-registered pharmacist.

Order within 12h 52m for next-day delivery

Royal Mail tracked delivery £2.99 per order

Epiduo Gel 0.1%/2.5% product packaging

Medically reviewed by Muhammad Abdul Jalil, Superintendent Pharmacist · GPhC Reg No: 2236161

Last reviewed

Epiduo Gel: Effective Acne Treatment

What is Epiduo Gel?

Epiduo Gel is a topical acne treatment specifically designed for acne vulgaris, a common skin condition characterised by blackheads, whiteheads, papules, and pustules. It is a combination medication containing adapalene (a retinoid) and benzoyl peroxide (an antimicrobial agent), making it a powerful dual-action solution for acne.

Epiduo is available without a prior prescription, but it must only be used after a professional diagnosis.

What Strengths of Epiduo Gel Are Available?

Epiduo Gel comes in two strengths:

  1. Epiduo 0.1% – Suitable for first-time users.
  2. Epiduo 0.3% (Epiduo Forte) – Contains a higher concentration of adapalene for more severe or persistent acne.

Both versions work in the same way, differing only in the concentration of the active ingredient.

How Does Epiduo Gel Work?

Acne develops when pores become clogged with oil (sebum), dirt, and bacteria, causing inflammation and the formation of spots. Hormonal changes, particularly during adolescence or premenstrual periods, often exacerbate this condition by increasing sebum production.

Key Active Ingredients in Epiduo Gel:

  1. Adapalene (Retinoid): Stimulates skin cell turnover to replace blocked pores with fresh, healthy skin. It also reduces inflammation, helping alleviate redness and swelling.
  2. Benzoyl Peroxide (Antimicrobial): Softens skin, unclogs pores, and kills acne-causing bacteria, preventing new breakouts.

This combination addresses the root causes of acne while reducing symptoms.

How to Use Epiduo Gel

Instructions for Application

  1. Clean and dry the affected skin before use.
  2. Apply a thin layer of gel to the affected area once daily, ideally at night.
  3. Wash your hands after applying.
  4. Avoid applying cosmetics immediately after use.

Important Notes:

  • Do not use the gel on broken, irritated, or damaged skin.
  • Avoid contact with the eyes, nostrils, and mouth; rinse thoroughly with water if contact occurs.
  • Do not apply more than the recommended amount, as this may increase the risk of side effects.

What Are the Possible Side Effects of Epiduo Gel?

Common Side Effects:

  • Dry skin
  • Scaling
  • Mild redness or burning sensations
  • Contact dermatitis

Less Common Side Effects:

  • Itching
  • Skin discolouration

If you experience severe or persistent side effects, discontinue use and consult a healthcare professional. Signs of an allergic reaction (e.g., rashes, breathing difficulties, facial swelling) require immediate medical attention.

Who Can Use Epiduo Gel?

Epiduo Gel is generally safe for most individuals. However, it is not suitable if you:

  • Are pregnant or trying to conceive.
  • Are allergic to any of its ingredients (e.g., adapalene or benzoyl peroxide).
  • Are already using other topical retinoids or benzoyl peroxide products.
  • Have undiagnosed or non-acne skin conditions.

Precautions When Using Epiduo Gel

  • Sun Sensitivity: Epiduo Gel can make your skin more sensitive to UV rays. Always use sunscreen and limit sun exposure while on this treatment.
  • Bleaching Effect: The gel can bleach clothing and hair, so take care during application.
  • Cosmetic Reactions: Avoid irritating skincare products and observe how your skin responds to cosmetics when using Epiduo.
  • Pregnancy: Do not use Epiduo if you are pregnant or breastfeeding without consulting a healthcare professional.

Can I Buy Epiduo Gel Online?

Yes, you can buy Epiduo Gel online safely and conveniently from Medihealth Direct. Complete a simple consultation form detailing your medical history and symptoms. Once approved by a UK-registered healthcare professional, your prescription will be issued, and the product will be dispatched from our in-house pharmacy.

Delivery Options for Epiduo Gel

Medihealth Direct offers several secure delivery options:

  • Next-Day Delivery: Free with Royal Mail for orders placed before the cut-off time.
  • Nominated-Day Delivery: Select your preferred delivery date.

Orders are dispatched in discreet packaging to ensure your privacy.

Epiduo Gel FAQs

How long does it take Epiduo Gel to work?

You may notice improvements within 4–8 weeks, but full results may take up to 12 weeks.

Can I use Epiduo with other acne treatments?

Avoid using Epiduo with other retinoids or benzoyl peroxide products, as this can increase irritation.

Is Epiduo Gel suitable for sensitive skin?

While it can be used on most skin types, it may cause dryness or irritation in sensitive skin. Start with a small application and monitor your skin’s reaction.

What should I do if I miss a dose?

Apply the next dose as usual. Do not double the application to make up for a missed dose.

Can I wear makeup while using Epiduo Gel?

Yes, but avoid applying cosmetics immediately after using Epiduo. Choose non-comedogenic (non-pore-clogging) products.

Transparent pricing

The price you see is the price you pay, no hidden fees.

Price
£59.99
What's included
  • Online consultation & prescription from a UK clinician
  • Discreet, tracked deliveryRoyal Mail tracked delivery is £2.99 per order, added at checkout.
  • Ongoing clinical support from our pharmacy team

You're only charged after a prescriber approves your consultation. If it's not right for you, you're not charged.

Delivery & packaging

  • Royal Mail tracked delivery
    £2.99 per order
  • Next-day
    Order by 2pm Monday to Friday and an approved order is dispatched the same day for next-working-day delivery.
  • Packaging
    Every parcel is plain and unbranded; temperature-sensitive medicines travel in insulated cold-chain packaging at no extra cost.

Questions before you start?

  • Call the pharmacy team
    0115 990 1203
    Mon–Fri, 9am–6pm
  • Email us
    hello@medihealthdirect.com
    We reply within one working day
  • Secure messages in your account
    Encrypted · replies within one working day
  • Ask Maya on the website
    Available any time, day or night
GPhC RegisteredUK Licensed MedicationNext Day DeliveryDiscreet & Confidential
Clinically reviewed by UK pharmacists
Discreet, plain packaging on every order
Next-day tracked delivery