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Melatonin

Melatonin, also sold under the brand name Circadin, is a prescription medication designed to treat short-term sleep issues, including insomnia and jet lag. Available in 2mg and 3mg tablets, it is a synthetic version of the natural hormone melatonin, helps regulate the body’s sleep-wake cycle.

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Dose guides: 2mg · 3mg

1
£31.992mg

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Prescription medication: subject to clinical review by a GPhC-registered pharmacist.

Order within 11h 53m for next-day delivery

Royal Mail tracked delivery £2.99 per order

Melatonin 2mg product packaging

Medically reviewed by Muhammad Abdul Jalil, Superintendent Pharmacist · GPhC Reg No: 2236161

Last reviewed

Melatonin (Circadin): A Natural Sleep Aid for Insomnia and Jet Lag

What is Melatonin (Circadin)?

Melatonin, also sold under the brand name Circadin, is a prescription medication designed to treat short-term sleep issues, including insomnia and jet lag. Available in 2mg and 3mg tablets, it is a synthetic version of the natural hormone melatonin, helps regulate the body’s sleep-wake cycle.

At Medihealth Direct, Melatonin is available for the treatment of primary insomnia and jet lag, offering a natural and safer alternative to traditional sleeping pills.

What is Melatonin Used For?

Melatonin tablets are primarily used for:

  1. Primary Insomnia
    • Improves sleep quality.
    • Reduces daytime sleepiness caused by lack of sleep.
  2. Jet Lag
    • Adjusts the sleep-wake cycle to match new time zones during travel.

Melatonin is most effective for older adults with naturally lower levels of melatonin. It is also prescribed off-label for adults under 55 for insomnia.

How Does Melatonin Work?

Melatonin is a hormone that plays a critical role in the body’s circadian rhythm, also known as the sleep-wake cycle.

  • When it gets dark, the brain’s pineal gland produces melatonin, signalling the body to sleep.
  • In the morning, light suppresses melatonin production, promoting alertness.

By supplementing natural melatonin levels, this medication helps regulate sleep patterns, making it easier to fall asleep and stay asleep.

Benefits of Melatonin Tablets

  • Improved Sleep: Helps increase total sleep time and reduces the time it takes to fall asleep.
  • Natural Aid: Mimics the body’s natural hormone, with a lower risk of severe drowsiness or addiction compared to traditional sleeping aids.
  • Safe for Short-Term Use: Effective for conditions like jet lag and short-term insomnia.

How to Take Melatonin

For Insomnia

  • Take one 2mg modified-release tablet 1-2 hours before bedtime.
  • Maximum treatment duration is 13 weeks.
  • If no improvement occurs, consult your healthcare professional for alternative treatments.

For Jet Lag

  • Take one 3mg immediate-release tablet 1-2 hours before bedtime at your destination.
  • Do not exceed 6mg daily, and limit use to 5 days.
  • Avoid taking tablets before 8 pm or after 4 am.

Missed Dose:

If you forget a dose but it is still nighttime, take it as soon as possible. Do not double up on doses to compensate.

Possible Side Effects

Melatonin is well-tolerated, with most side effects being mild and temporary.

Common Side Effects

  • Headaches.
  • Joint pain (arthralgia).
  • Nausea or stomach discomfort.
  • Mild drowsiness or fatigue.

Serious Side Effects (Rare):

  • Allergic reactions (e.g., swelling of the face, lips, or throat).
  • Chest pain.

If you experience persistent or severe side effects, contact your healthcare professional immediately.

Precautions When Taking Melatonin

  • Pregnancy and Breastfeeding: Consult your healthcare professional before use.
  • Autoimmune Diseases: Avoid use unless prescribed.
  • Smoking: This may reduce the effectiveness of melatonin.
  • Operating Machinery: As melatonin can cause drowsiness, avoid driving or using heavy machinery after taking it.
  • Lifestyle Adjustments:
    • Avoid caffeine and heavy meals before bedtime.
    • Create a quiet, dark, and comfortable sleeping environment.

Drug Interactions

Melatonin may interact with certain medications, potentially altering its effectiveness. Inform your healthcare professional if you are taking:

  • Antidepressants (e.g., fluvoxamine).
  • Hormonal contraceptives or HRT.
  • Epilepsy medications.
  • NSAIDs (e.g., ibuprofen).
  • Antibiotics.
  • Medications for blood pressure or drug addiction.

For a full list, refer to the patient leaflet included with the medication.

How to Buy Melatonin Online Safely

You can purchase Melatonin at Medihealth Direct following a simple online consultation.

  1. Consultation: Complete a quick medical questionnaire.
  2. Healthcare Professional Review: Our UK-registered healthcare professional will assess your suitability.
  3. Fast Delivery: Receive your medication with next-day delivery in discreet packaging.

Melatonin is prescription-only and not available over the counter in the UK.

Melatonin FAQs

Is Melatonin addictive?

No, Melatonin is non-addictive, making it safer than traditional sleeping aids.

How long does Melatonin stay in the body?

Melatonin typically stays in the body for 4-5 hours, but this can vary based on age and dosage.

Can I take Melatonin long-term?

Long-term effects are not well studied. Use Melatonin only as directed by your healthcare professional.

Can I overdose on Melatonin?

Overdosing is unlikely but may cause drowsiness, nausea, or headaches. Always stick to the prescribed dose.

Is Melatonin safe to buy online?

Yes, when purchased from reputable providers like Medihealth Direct, Melatonin is safe and regulated.

Transparent pricing

The price you see is the price you pay, no hidden fees.

From
£31.99
Dose & price path
  • 2mg£31.99
  • 3mg£34.99

Your prescriber sets the right strength for you. You only ever pay for the dose you're prescribed.

What's included
  • Online consultation & prescription from a UK clinician
  • Discreet, tracked deliveryRoyal Mail tracked delivery is £2.99 per order, added at checkout.
  • Ongoing clinical support from our pharmacy team

You're only charged after a prescriber approves your consultation. If it's not right for you, you're not charged.

Delivery & packaging

  • Royal Mail tracked delivery
    £2.99 per order
  • Next-day
    Order by 2pm Monday to Friday and an approved order is dispatched the same day for next-working-day delivery.
  • Packaging
    Every parcel is plain and unbranded; temperature-sensitive medicines travel in insulated cold-chain packaging at no extra cost.

Questions before you start?

  • Call the pharmacy team
    0115 990 1203
    Mon–Fri, 9am–6pm
  • Email us
    hello@medihealthdirect.com
    We reply within one working day
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  • Ask Maya on the website
    Available any time, day or night
GPhC RegisteredUK Licensed MedicationNext Day DeliveryDiscreet & Confidential
Clinically reviewed by UK pharmacists
Discreet, plain packaging on every order
Next-day tracked delivery